Toward C13 hyperpolarized biomarkers produced by thermal mixing with hyperpolarized X129e
نویسندگان
چکیده
منابع مشابه
Observation of anomalously long-lived hyperpolarized C13 states in parahydrogen-induced polarization
Introduction: Hyperpolarized contrast media based on nuclei such as C yield significant enhancements of signal-to-noise ratio in MRI (1). These agents are beginning to show promise for a variety of applications, including real-time metabolic imaging (2) and cancer imaging (3). One challenge to the widespread application of these agents is the relatively short spin-lattice (T1) relaxation time o...
متن کاملHyperpolarized MR imaging: neurologic applications of hyperpolarized metabolism.
Hyperpolarization is the general term for a method of enhancing the spin-polarization difference of populations of nuclei in a magnetic field. No less than 5 distinct techniques (dynamic nuclear polarization [DNP]; parahydrogen-induced polarization-parahydrogen and synthesis allow dramatically enhanced nuclear alignment [PHIP-PASADENA]; xenon/helium polarization transfer; Brute Force; (1)H hype...
متن کاملNon-thermal nuclear magnetic resonance quantum computing using hyperpolarized xenon
Current experiments in liquid-state nuclear magnetic resonance ~NMR! quantum computing are limited by low initial polarization. To address this problem, we have investigated the use of optical pumping techniques to enhance the polarization of a 2-qubit NMR quantum computer ~C and H in CHCl3!. We have generalized the procedure for effective pure state preparation in order to efficiently use the ...
متن کامل13C Hyperpolarized Anticoagulants
J. Bargon, J. Bernarding, R. Rizi, H-W. Spiess, K. Münnemann, M. Roth, and U. Bommerich Institute of Physical and Theoretical Chemistry, University of Bonn, Bonn, NRW, Germany, Institute of Biometry, University of Magdeburg, Magdeburg, Germany, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States, NMR, Max-Planck Institute of Polymers, Mainz, Germany, I...
متن کاملTransportable hyperpolarized metabolites
Nuclear spin hyperpolarization of 13C-labelled metabolites by dissolution dynamic nuclear polarization can enhance the NMR signals of metabolites by several orders of magnitude, which has enabled in vivo metabolic imaging by MRI. However, because of the short lifetime of the hyperpolarized magnetization (typically <1 min), the polarization process must be carried out close to the point of use. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Chemical Physics
سال: 2009
ISSN: 0021-9606,1089-7690
DOI: 10.1063/1.3181062